Recombinant humaan TNFSF10-eiwit
Gecertificeerd

Recombinant humaan TNFSF10-eiwit

Catalog #: PH0148E2
Maat: 20 µg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

Description

In the field of cell biology, TNF-related apoptosis-inducing ligand (TRAIL), is a protein functioning as a ligand that induces the process of cell death called apoptosis. TRAIL is a cytokine that is produced and secreted by most normal tissue cells. It causes apoptosis primarily in tumor cells, by binding to certain death receptors. TRAIL and its receptors have been used as the targets of several anti-cancer therapeutics since the mid-1990s, such as Mapatumumab. However, as of 2013, these have not shown significant survival benefit. TRAIL has also been implicated as a pathogenic or protective factor in various pulmonary diseases, particularly pulmonary arterial hypertension. TRAIL has also been designated CD253 (cluster of differentiation 253) and TNFSF10 (tumor necrosis factor (ligand) superfamily, member 10) .

Purity

Greater than 95% by SDS-PAGE

Form

Lyophilized

Buffer

0.2 μm filtered ?40mM Tris, 0.3 M NaCl, pH 7.0

Storage Conditions

-70°C

Beschrijving

In the field of cell biology, TNF-related apoptosis-inducing ligand (TRAIL), is a protein functioning as a ligand that induces the process of cell death called

Specificaties

ProductnaamRecombinant humaan TNFSF10-eiwit
Categorie
Beschikbare grootte20 µg
CatalogusnummerPH0148E2