Recombinant humaan TPST2-eiwit

TPST2, also known as protein-tyrosine sulfotransferase 2, is the enzyme that catalyzes the sulfation reaction of protein tyrosines, a post-translational modification of proteins. This protein is a type II integral membrane protein found in the Golgi body. Compared to TPST1, TPST2 has similar tissue distribution and overlapping substrate specificity. In contrast to TPST1-/- males with normal fertility in mice, TPST2-/- males are infertile due to severe defects in sperm motility. Recombinant human TPST2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Protein-tyrosine sulfotransferase 2, TANGO13B

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

40.4 kDa (361aa)

TPST2, Protein-tyrosine sulfotransferase 2, TANGO13B, ATGP3332-10 µg, ATGP3332-20 µg, ATGP3332-50 µg, ATGP3332-100 µg, ATGP3332-250 µg, ATGP3332-500 µg, ATGP3332-1 mg, ATGP3332-10, ATGP3332-20, ATGP3332-50, ATGP3332-100, ATGP3332-250, ATGP3332-500, ATGP3332-1

Danan LM., et al. (2008) . J Am Soc Mass Spectrom. 19 (10) :1459-1466.; ; Kehoe J.W. and Bertozzi C.R. (2000) Chemistry & Biology. 7:57-61.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_001008566.1

O60704

Human

Ala

QQVLECR AVLAGLRSPR GAMRPEQEEL VMVGTNHVEY RYGKAMPLIF VGGVPRSGTT LMRAMLDAHP EVRCGEETRI IPRVLAMRQA WSKSGREKLR LDEAGVTDEV LDAAMQAFIL EVIAKHGEPA RVLCNKDPFT LKSSVYLSRL FPNSKFLLMV RDGRASVHSM ITRKVTIAGF DLSSYRDCLT KWNKAIEVMY AQCMEVGKEK CLPVYYEQLV LHPRRSLKLI LDFLGIAWSD AVLHHEDLIG KPGGVSLSKI ERSTDQVIKP VNLEALSKWT GHIPGDVVRD MAQIAPMLAQ LGYDPYANPP NYGNPDPFVI NNTQRVLKGD YKTPANLKGY FQVNQNSTSS HLGSS