Recombinant humaan TRAILR3/TNFRSF10C eiwit

TNFRSF10C also known as tumor necrosis factor receptor superfamily member 10C is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. Recombinant human TNFRSF10C, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Tumor necrosis factor receptor superfamily member 10C, Antagonist decoy receptor for TRAIL/Apo-2L, Decoy TRAIL receptor without death domain, Decoy receptor 1, DcR1, Lymphocyte inhibitor of TRAIL, TNF-related apoptosis-inducing ligand receptor 3, TRAIL receptor 3, TRAIL-R3, CD263, LIT, TRAILR3, TRID, TRAIL receptor without an intracellular domain

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by BCA assay)

> 90% by SDS-PAGE

24.6 kDa (234aa) confirmed by MALDI-TOF

TRAIL R3, TNFRSF10C, Tumor necrosis factor receptor superfamily member 10C, Tumor necrosis factor receptor superfamily member 10C, CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID, ATGP3055-10 µg, ATGP3055-20 µg, ATGP3055-50 µg, ATGP3055-100 µg, ATGP3055-250 µg, ATGP3055-500 µg, ATGP3055-1 mg, ATGP3055-10, ATGP3055-20, ATGP3055-50, ATGP3055-100, ATGP3055-250, ATGP3055-500, ATGP3055-1

Venza M., et al. (2013) Biochem. Biophys. Res. Commun. 441 (4), 743-750

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Apoptosis

NP_003832

O14798

Human

ATTARQE EVPQQTVAPQ QQRHSFKGEE CPAGSHRSEH TGACNPCTEG VDYTNASNNE PSCFPCTVCK SDQKHKSSCT MTRDTVCQCK EGTFRNENSP EMCRKCSRCP SGEVQVSNCT SWDDIQCVEE FGANATVETP AAEETMNTSP GTPAPAAEET MNTSPGTPAP AAEETMTTSP GTPAPAAEET MTTSPGTPAP AAEETMTTSP GTPA