Recombinant humaan TRAPPC2-eiwit

TRAPPC2 is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, this protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in TRAPPC2 are a cause of spondyloepiphyseal dysplasia tarda (SEDT) . Recombinant human TRAPPC2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

ZNF547L, TRS20, TRAPPC2P1, Trafficking protein particle complex subunit 2, Spondyloepiphyseal dysplasia late, SEDT, Sedlin, SEDL, MIP2A, hYP38334

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

18.8 kDa (163aa) confirmed by MALDI-TOF

TRAPPC2, Trafficking protein particle complex subunit 2, hYP38334, MIP2A, SEDL, SEDT, TRAPPC2P1, TRS20, ZNF547L, ATGP1795-10 µg, ATGP1795-20 µg, ATGP1795-50 µg, ATGP1795-100 µg, ATGP1795-250 µg, ATGP1795-500 µg, ATGP1795-1 mg, ATGP1795-10, ATGP1795-20, ATGP1795-50, ATGP1795-100, ATGP1795-250, ATGP1795-500, ATGP1795-1

Gecz J, Shaw MA, et al. (2003) . Gene. 27; ;320:137-44.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 1mM DTT

Signal Transduction

NP_055378

P0DI81

Human

MSGSFYF VIVGHHDNPV FEMEFLPAGK AESKDDHRHL NQFIAHAALD LVDENMWLSN NMYLKTVDKF NEWFVSAFVT AGHMRFIMLH DIRQEDGIKN FFTDVYDLYI KFSMNPFYEP NSPIRSSAFD RKVQFLGKKH LLS