Recombinant humaan TRAX-eiwit

TSNAX is a protein which specifically interacts with translin, a DNA-binding protein that binds consensus sequences at breakpoint junctions of chromosomal translocations. The protein contains bipartite nuclear targeting sequences that may provide nuclear transport for translin, which lacks any nuclear targeting motifs. Recombinant human TSNAX protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Translin-associated protein X, TRAX

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

35 kDa (313aa) confirmed by MALDI-TOF

TSNAX, Translin-associated protein X, TRAX, , ATGP1819-10 µg, ATGP1819-20 µg, ATGP1819-50 µg, ATGP1819-100 µg, ATGP1819-250 µg, ATGP1819-500 µg, ATGP1819-1 mg, ATGP1819-010, ATGP1819-020, ATGP1819-050, ATGP1819-100, ATGP1819-250, ATGP1819-500, ATGP1819-01M

Chennathukuzhi VM, Kurihara Y, et al. (2001) . J Biol Chem. 276 (16) :13256-63.; ; Thomson PA, Wray NR, et al. (2005) . Mol Psychiatry. 10 (7) :657-68, 616.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 50 mM Imidazole, 0.1mM PMSF

Epigenomics (Transcription & Translation)

NP_005990.1

Q99598

Human

MSNKEGS GGFRKRKHDN FPHNQRREGK DVNSSSPVML AFKSFQQELD ARHDKYERLV KLSRDITVES KRTIFLLHRI TSAPDMEDIL TESEIKLDGV RQKIFQVAQE LSGEDMHQFH RAITTGLQEY VEAVSFQHFI KTRSLISMDE INKQLIFTTE DNGKENKTPS SDAQDKQFGT WRLRVTPVDY LLGVADLTGE LMRMCINSVG NGDIDTPFEV SQFLRQVYDG FSFIGNTGPY EVSKKLYTLK QSLAKVENAC YALKVRGSEI PKHMLADVFS VKTEMIDQEE GIS