Recombinant humaan TREX2-eiwit

TREX2 is an enzyme containing 3-prime-to-5-prime exonuclease activity and removes mismatched, modified, fragmented, and normal nucleotides to generate the appropriate 3-prime termini for subsequent steps in the DNA metabolic pathways. This enzyme is involved in DNA replication, repair, and recombination. Recombinant human TREX2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Three prime repair exonuclease 2

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

28.0 kDa (256aa) confirmed by MALDI-TOF

TREX2, Three prime repair exonuclease 2, ATGP0970-10 µg, ATGP0970-20 µg, ATGP0970-50 µg, ATGP0970-100 µg, ATGP0970-250 µg, ATGP0970-500 µg, ATGP0970-1 mg, ATGP0970-10, ATGP0970-20, ATGP0970-50, ATGP0970-100, ATGP0970-250, ATGP0970-500, ATGP0970-1

Parra D., et al. (2009) Cancer Res. 69 (16) :6676-84.; ; Perrino FW., et al. (2008) J Biol Chem. 283 (31) :21441-52.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 30% glycerol

Enzymes & Proteases

NP_542432

Q9BQ50

Human

MGSSHHHHHH SSGLVPRGSH MSEAPRAETF VFLDLEATGL PSVEPEIAEL SLFAVHRSSL ENPEHDESGA LVLPRVLDKL TLCMCPERPF TAKASEITGL SSEGLARCRK AGFDGAVVRT LQAFLSRQAG PICLVAHNGF DYDFPLLCAE LRRLGARLPR DTVCLDTLPA LRGLDRAHSH GTRARGRQGY SLGSLFHRYF RAEPSAAHSA EGDVHTLLLI FLHRAAELLA WADEQARGWA HIEPMYLPPD DPSLEA