Recombinant humaan TrkB-eiwit

NTRK2, also known as BDNF/NT-3 growth factors receptor, is a receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. It plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation. Recombinant human NTRK2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

GP145-TrkB, trk-B, TRKB, NTRK2

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

45.2 kDa (407aa)

TrkB, GP145-TrkB, trk-B, TRKB, NTRK2, ATGP3264-10 µg, ATGP3264-20 µg, ATGP3264-50 µg, ATGP3264-100 µg, ATGP3264-250 µg, ATGP3264-500 µg, ATGP3264-1 mg, ATGP3264-10, ATGP3264-20, ATGP3264-50, ATGP3264-100, ATGP3264-250, ATGP3264-500, ATGP3264-1

Yeo GS., et al. (2004) Nat Neurosci. 7:1187-1189.; ; Banfield MJ., et al. (2001) Structure. 9:1191-1199.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Neuroscience

NP_001018074.1

Q16620

Human