Recombinant humaan Troponine I2/TNNI2-eiwit

Troponin I, fast skeletal muscle, also known as TNNI2, is a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in TNNI2 cause myopathy and distal arthrogryposis type 2B. Recombinant human TNNI2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Troponin I fast skeletal muscle, AMCD2B, DA2B, FSSV, fsTnI

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

23.5 kDa (202aa)

TNNI2, Troponin I fast skeletal muscle, Troponin I, fast skeletal muscle, AMCD2B, DA2B, FSSV, fsTnI, ATGP1810-10 µg, ATGP1810-20 µg, ATGP1810-50 µg, ATGP1810-100 µg, ATGP1810-250 µg, ATGP1810-500 µg, ATGP1810-1 mg, ATGP1810-10, ATGP1810-20, ATGP1810-50, ATGP1810-100, ATGP1810-250, ATGP1810-500, ATGP1810-1

Ausoni S., et al. (1994) J Biol Chem. 269:339-346.; ; Potter J D., et al. (1995) J Biol Chem. 270:2557-2562.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol, 0.2M NaCl

Cytoskeleton

NP_001139301

P48788

Human

MGSSHHHHHH SSGLVPRGSH MGDEEKRNRA ITARRQHLKS VMLQIAATEL EKEESRREAE KQNYLAEHCP PLHIPGSMSE VQELCKQLHA KIDAAEEEKY DMEVRVQKTS KELEDMNQKL FDLRGKFKRP PLRRVRMSAD AMLKALLGSK HKVCMDLRAN LKQVKKEDTE KERDLRDVGD WRKNIEEKSG MEGRKKMFES ES