Recombinant humaan TSN-eiwit

Translin, also known TSN, is a DNA and RNA binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin forms a ring-shaped structure, which is responsible for DNA binding, and also contains a leucine zipper motif, which is thought to enable translin to form dimers. Translin exports specific mRNAs out of the nucleus, supported by its localization in both the nuclei and cytoplasm of neurons, and regulates their translation. Recombinant human Translin protein, was expressed in E. coli and purified by using conventional chromatography techniques.

Translin, BCLF-1, RCHF1, REHF-1, TBRBP, TRSLN

E.coli

Human

Non-Tagged

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

26.1 kDa (228aa) confirmed by MALDI-TOF

TSN, Translin, BCLF-1, RCHF1, REHF-1, TBRBP, TRSLN, ATGP0761-10 µg, ATGP0761-20 µg, ATGP0761-50 µg, ATGP0761-100 µg, ATGP0761-250 µg, ATGP0761-500 µg, ATGP0761-1 mg, ATGP0761-10, ATGP0761-20, ATGP0761-50, ATGP0761-100, ATGP0761-250, ATGP0761-500, ATGP0761-1

Gu W., et al. (1998) Mol Reprod Dev. 49:219-228.; ; Aoki K., et al. (1999) FEBS Lett. 443:363-366.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol 100 mM NaCl

Transportation

NP_004613

Q15631

Human

MSVSEIFVEL QGFLAAEQDI REEIRKVVQS LEQTAREILT LLQGVHQGAG FQDIPKRCLK AREHFGTVKT HLTSLKTKFP AEQYYRFHEH WRFVLQRLVF LAAFVVYLET ETLVTREAVT EILGIEPDRE KGFHLDVEDY LSGVLILASE LSRLSVNSVT AGDYSRPLHI STFINELDSG FRLLNLKNDS LRKRYDGLKY DVKKVEEVVY DLSIRGFNKE TAAACVEK