Recombinant humaan TSPAN7-eiwit

TSPAN7, as known as tetraspanin-7, is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Also, it is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. More recently, it has been identified as a key immune system target in type 1 diabetes. Recombinant human TSPAN7, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Tetraspanin-7, TSPAN7, A15, CCG-B7, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2, TM4SF2b

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

12.6 kDa (110aa)

TSPAN7, ATGP3554-10 µg, ATGP3554-20 µg, ATGP3554-50 µg, ATGP3554-100 µg, ATGP3554-250 µg, ATGP3554-500 µg, ATGP3554-1 mg, ATGP3554-10, ATGP3554-20, ATGP3554-50, ATGP3554-100, ATGP3554-250, ATGP3554-500, ATGP3554-1

Wuttig D., et al, (2012) Int. J. Cancer 131:e693-704.; ; Bassani S., et al, (2012) Neuron 73:1143-1158.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Metabolism

NP_004606

P41732

Human

Ala

RHEIKDT FLRTYTDAMQ TYNGNDERSR AVDHVQRSLS CCGVQNYTNW STSPYFLEHG IPPSCCMNET DCNPQDLHNL TVAATKVNQK GCYDLVTSFM ETNM