Recombinant humaan TXNL4A-eiwit

Thioredoxin-like 4A, also known as TXNL4A, belongs to the Dim protein family. TXNL4A is a 142 amino acid protein that plays an essential role in pre-mRNA splicing. Due to a failure to express early zygotic transcripts, deletion of the gene encoding TXNL4A in Schizosaccharomyces pombe leads to embryonal lethality during gastrulation. Localized to the nucleus, TXNL4A interacts with hnRNP F, hnRNP H2, Cas-L and PQBP-1 to effect gene expression. Recombinant human TXNL4A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Thioredoxin-like 4A, DIB1, DIM1, HsT161, TXNL4, u5-15kD

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

19.3 kDa (166aa) confirmed by MALDI-TOF

TXNL4A, Thioredoxin-like 4A, DIB1, DIM1, HsT161, TXNL4, u5-15kD, ATGP1539-10 µg, ATGP1539-20 µg, ATGP1539-50 µg, ATGP1539-100 µg, ATGP1539-250 µg, ATGP1539-500 µg, ATGP1539-1 mg, ATGP1539-10, ATGP1539-20, ATGP1539-50, ATGP1539-100, ATGP1539-250, ATGP1539-500, ATGP1539-1

Zhang Y Z., et al. (1999) Physiol Genomics. 1:109-118.; ; Zhang Y Z., et al. (2000) Gene. 257: 33-43.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT

Epigenomics (Transcription & Translation)

NP_006692

P83876

Human

MGSSHHHHHH SSGLVPRGSH MGSHMSYMLP HLHNGWQVDQ AILSEEDRVV VIRFGHDWDP TCMKMDEVLY SIAEKVKNFA VIYLVDITEV PDFNKMYELY DPCTVMFFFR NKHIMIDLGT GNNNKINWAM EDKQEMVDII ETVYRGARKG RGLVVSPKDY STKYRY