Recombinant humaan ULBP-1-eiwit

ULBP1, also known as NKG2D ligand 1, is a member of a family of cell-surface proteins that function as ligands for human NKG2D. It is unconventional MHC class I-like molecules exploited by viruses and cancer. Its ligand Methylation contributes to immune system evasion in acute myeloid leukemia. It is independent predictors of good prognosis in cervical cancer. Recombinant human ULBP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Human ULBP-1 is coated at 10 µg/mL (100 ul/well) can bind NKG2D (CAT# ATGP3662) in a Functional ELISA assay.

UL16 binding protein 1, ALCAN-beta, NKG2D ligand 1, N2DL-1, NKG2DL1, Retinoic acid early transcript 1I, RAET1I

Baculovirus

Human

His-Tag

SDS-PAGE, Bioactivity

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

Measured by its binding ability in a functional ELISA with Human NKG2D (CAT# ATGP3662) .

23.4 kDa (200aa)

ULBP1, NKG2D ligand 1, ULBP1, N2DL-1, NKG2DL1, RAET1I, ATGP3479-10 µg, ATGP3479-20 µg, ATGP3479-50 µg, ATGP3479-100 µg, ATGP3479-250 µg, ATGP3479-500 µg, ATGP3479-1 mg, ATGP3479-10, ATGP3479-20, ATGP3479-50, ATGP3479-100, ATGP3479-250, ATGP3479-500, ATGP3479-1

Baragano Raneros A., et al. (2015) Genes Immun. 16:71-82.; ; Cerwenka A., et al. (2003) Tissue Antigens. 61:335-343.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_079494

Q9BZM6

Human

Ala

GWVDTHC LCYDFIITPK SRPEPQWCEV QGLVDERPFL HYDCVNHKAK AFASLGKKVN VTKTWEEQTE TLRDVVDFLK GQLLDIQVEN LIPIEPLTLQ ARMSCEHEAH GHGRGSWQFL FNGQKFLLFD SNNRKWTALH PGAKKMTEKW EKNRDVTMFF QKISLGDCKM WLEEFLMYWE QMLDPTKPPS LAPG