Recombinant humaan ULBP-4/RAET1E eiwit

RAET1E belongs to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24. 2-q25. 3. RAET1E and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human RAET1E protein, fused to His-tag at N-terminus, was expressed in E. coli.

Retinoic acid early transcript 1E, Lymphocyte effector toxicity activation ligand, NKG2D ligand 4, N2DL-4, NKG2DL4, RAE-1-like transcript 4, UL16-binding protein 4, LETAL, N2DL4, ULBP4

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

24.9 kDa (219aa)

ULBP4, RAET1E, NKG2D ligand 4, bA350J20.7, LETAL, N2DL-4, NKG2DL4, RAET1E2, RL-4, uLBP4, ATGP1820-10 µg, ATGP1820-20 µg, ATGP1820-50 µg, ATGP1820-100 µg, ATGP1820-250 µg, ATGP1820-500 µg, ATGP1820-1 mg, ATGP1820-10, ATGP1820-20, ATGP1820-50, ATGP1820-100, ATGP1820-250, ATGP1820-500, ATGP1820-1

McGilvray, R.W., et al. (2010) Int. J. Cancer 127 (6), 1412-1420; ; Antoun, A., et al. (2010) Hum. Immunol. 71 (6), 610-620;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Immunology

NP_631904

Q8TD07

Human

MGSSHHHHHH SSGLVPRGSH MGSMHSLCFN FTIKSLSRPG QPWCEAQVFL NKNLFLQYNS DNNMVKPLGL LGKKVYATST WGELTQTLGE VGRDLRMLLC DIKPQIKTSD PSTLQVEMFC QREAERCTGA SWQFATNGEK SLLFDAMNMT WTVINHEASK IKETWKKDRG LEKYFRKLSK GDCDHWLREF LGHWEAMPEP TVSPVNASDI HWSSSSLPD