Recombinant humaan uPAR-eiwit

PLAUR, as known as urokinase plasminogen activator surface receptor isoform 1, is one of two activators that converts the extracellular zymogen plasminogen to plasmin, a serine protease that is involved in a variety of normal and pathological processes that require cell migration and/or tissue destruction. This protein is synthesized and released from cells as a single-chain proenzyme with limited enzymatic activity and is converted to an active two-chain disulfide-linked active enzyme by plasmin and other specific proteinases. Recombinant human PLAUR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Urokinase plasminogen activator surface receptor isoform 1, PLAUR, CD87, U-PAR, UPAR, URKR, CD 87, CD87, CD87 antigen, MO 3, MO3, Monocyte activation antigen Mo3, Plasminogen activator receptor urokinase, Plasminogen activator urokinase receptor, PLAUR, U PAR, u plasminogen activator receptor, U-PAR, u-plasminogen activator receptor form 2, UPA receptor, uPAR, UPAR_HUMAN, Urinary plasminogen activator receptor, URKR, Urokinase plasminogen activator receptor, Urokinase plasminogen activator surface receptor, urokinase-type plasminogen activator (uPA) receptor

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

32.5 kDa (291aa)

UPAR, Urokinase plasminogen activator surface receptor isoform 1 , PLAUR, CD87, U-PAR, UPAR, URKR, CD 87, CD87CD87 antigen, MO 3, MO3, Monocyte activation antigen Mo3, Plasminogen activator receptor urokinase, Plasminogen activator urokinase receptorPLAUR, U PAR, u plasminogen activator receptorU-PAR, u-plasminogen activator receptor form 2, UPA receptor, uPAR, UPAR_HUMAN, Urinary plasminogen activator receptor, URKR, Urokinase plasminogen activator receptor, Urokinase plasminogen activator surface receptor, urokinase-type plasminogen activator (uPA) receptor, ATGP3409-10 µg, ATGP3409-20 µg, ATGP3409-50 µg, ATGP3409-100 µg, ATGP3409-250 µg, ATGP3409-500 µg, ATGP3409-1 mg, ATGP3409-10, ATGP3409-20, ATGP3409-50, ATGP3409-100, ATGP3409-250, ATGP3409-500, ATGP3409-1

Persson M., et al, (2014) Stroke 45:18-23.; ; Zhuang T., et al, (2013) BMC Cancer 13:590.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_002650

Q03405

Human

Leu23

LRCMQCKTNG DCRVEECALG QDLCRTTIVR LWEEGEELEL VEKSCTHSEK TNRTLSYRTG LKITSLTEVV CGLDLCNQGN SGRAVTYSRS RYLECISCGS SDMSCERGRH QSLQCRSPEE QCLDVVTHWI QEGEEGRPKD DRHLRGCGYL PGCPGSNGFH NNDTFHFLKC CNTTKCNEGP ILELENLPQN GRQCYSCKGN STHGCSSEET FLIDCRGPMN QCLVATGTHE PKNQSYMVRG CATASMCQHA HLGDAFSMNH IDVSCCTKSG CNHPDLDVQY RSGLEHHHHH H