Recombinant humaan Uridine-cytidine kinase 1/UCK1-eiwit

UCK1 is a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (uMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine ribonucleosides. This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms. Recombinant human uCK1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

URK1, Cytidine monophosphokinase 1, Uridine monophosphokinase 1

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

17.5 kDa (152aa)

URK1, Uridine-cytidine kinase 1 isoform a, Uridine cytidine kinase 1 isoform a, Uridine monophosphokinase 1, uCK1, RP11-334J6.5, RP11 334J6.5, FLJ12255, Cytidine monophosphokinase 1, ATGP2692-10 µg, ATGP2692-20 µg, ATGP2692-50 µg, ATGP2692-100 µg, ATGP2692-250 µg, ATGP2692-500 µg, ATGP2692-1 mg, ATGP2692-010, ATGP2692-020, ATGP2692-050, ATGP2692-100, ATGP2692-250, ATGP2692-500, ATGP2692-01M

Van Rompay AR. et al. (1999) Mol. Pharmacol. 56:562-569.; ; Pearman AT. et al. (2001) Life Sci. 69:2361-2370.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Epigenomics (Transcription & Translation)

NP_113620.1

Q9HA47

Human

MGSSHHHHHH SSGLVPRGSH MFYSQEIRDM FHLRLFVDTD SDVRLSRRVL RDVRRGRDLE QILTQYTTFV KPAFEEFCLP TKKYADVIIP RGVDNMVAIN LIVQHIQDIL NGDICKWHRG GSNGRSYKRT FSEPGDHPGM LTSGKRSHLE SS