Recombinant humaan USAG1-eiwit

SOSTDC1 is a member of the sclerostin family and an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. Recombinant human SOSTDC1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Sclerostin domain-containing protein 1, CDA019, ECTODIN, uSAG1

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

23 kDa (206aa)

USAG1, Sclerostin domain-containing protein 1, CDA019, ECTODIN, uSAG1, ATGP1905-10 µg, ATGP1905-20 µg, ATGP1905-50 µg, ATGP1905-100 µg, ATGP1905-250 µg, ATGP1905-500 µg, ATGP1905-1 mg, ATGP1905-10, ATGP1905-20, ATGP1905-50, ATGP1905-100, ATGP1905-250, ATGP1905-500, ATGP1905-1

Yanagita M, Oka M, et al. (2004) . Biochem Biophys Res Commun. 316 (2) :490-500.; ; Goto M, et al. (2004) . J Biol Chem. 279 (40) :42128-38.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Signal Transduction

NP_056279

Q6X4U4

Human

FKNDATE ILYSHVVKPV PAHPSSNSTL NQARNGGRHF SNTGLDRNTR VQVGCRELRS TKYISDGQCT SISPLKELVC AGECLPLPVL PNWIGGGYGT KYWSRRSSQE WRCVNDKTRT QRIQLQCQDG STRTYKITVV TACKCKRYTR QHNESSHNFE SMSPAKPVQH HRERKRASKS SKHSMS