Recombinant humaan UTP23 eiwit

RRNA-processing protein uTP23 homolog, also known as uTP23, is a small subunit (SSu) processome component. The SSu processome is a complex involved in ribosome biogenesis and is required for pre-18S rRNA maturation. uTP23 is required for the first three cleavage steps in 18S rRNA maturation. In addition, single-point mutations in the conserved putative active site of utp24 but not utp23 abrogate its function in ribosome biogenesis. Recombinant human uTP23 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

RRNA-processing protein uTP23 homolog, C8orf53

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

30.8 kDa (272aa) confirmed by MALDI-TOF

UTP23, rRNA-processing protein uTP23 homolog, C8orf53, ATGP1744-10 µg, ATGP1744-20 µg, ATGP1744-50 µg, ATGP1744-100 µg, ATGP1744-250 µg, ATGP1744-500 µg, ATGP1744-1 mg, ATGP1744-10, ATGP1744-20, ATGP1744-50, ATGP1744-100, ATGP1744-250, ATGP1744-500, ATGP1744-1

Bleichert F., et al. (2006) Proc Natl Acad Sci uSA. 103 (25) :9464-9; ; Bernstein K A., et al. (2004) Eukaryotic Cell. 3: 1619-1626.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol,1mM DTT

Epigenomics (Transcription & Translation)

NP_115710

Q9BRU9

Human

MGSSHHHHHH SSGLVPRGSH MGSMKITRQK HAKKHLGFFR NNFGVREPYQ ILLDGTFCQA ALRGRIQLRE QLPRYLMGET QLCTTRCVLK ELETLGKDLY GAKLIAQKCQ VRNCPHFKNA VSGSECLLSM VEEGNPHHYF VATQDQNLSV KVKKKPGVPL MFIIQNTMVL DKPSPKTIAF VKAVESGQLV SVHEKESIKH LKEEQGLVKN TEQSRRKKRK KISGPNPLSC LKKKKKAPDT QSSASEKKRK RKRIRNRSNP KVLSEKQNAE GE