Recombinant humaan VCAM-1/CD106-eiwit

VCAM1 is a member of the Ig superfamily and is a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Recombinant human VCAM1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Vascular cell adhesion protein 1 isoform, VCAM1, CD106, INCAM-100

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

76 kDa (695aa)

VCAM1, CD106, Vascular cell adhesion molecule 1, CD106; DKFZp 779G2333; INCAM-100; MGC99561, ATGP1573-10 µg, ATGP1573-20 µg, ATGP1573-50 µg, ATGP1573-100 µg, ATGP1573-250 µg, ATGP1573-500 µg, ATGP1573-1 mg, ATGP1573-10, ATGP1573-20, ATGP1573-50, ATGP1573-100, ATGP1573-250, ATGP1573-500, ATGP1573-1

Wu TC (2007) Cancer Res. 67 (13) : 6003-6.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Cancer

NP_001069

P19320

Human

MGSSHHHHHH SSGLVPRGSH MFKIETTPES RYLAQIGDSV SLTCSTTGCE SPFFSWRTQI DSPLNGKVTN EGTTSTLTMN PVSFGNEHSY LCTATCESRK LEKGIQVEIY SFPKDPEIHL SGPLEAGKPI TVKCSVADVY PFDRLEIDLL KGDHLMKSQE FLEDADRKSL ETKSLEVTFT PVIEDIGKVL VCRAKLHIDE MDSVPTVRQA VKELQVYISP KNTVISVNPS TKLQEGGSVT MTCSSEGLPA PEIFWSKKLD NGNLQHLSGN ATLTLIAMRM EDSGIYVCEG VNLIGKNRKE VELIVQEKPF TVEISPGPRI AAQIGDSVML TCSVMGCESP SFSWRTQIDS PLSGKVRSEG TNSTLTLSPV SFENEHSYLC TVTCGHKKLE KGIQVELYSF PRDPEIEMSG GLVNGSSVTV SCKVPSVYPL DRLEIELLKG ETILENIEFL EDTDMKSLEN KSLEMTFIPT IEDTGKALVC QAKLHIDDME FEPKQRQSTQ TLYVNVAPRD TTVLVSPSSI LEEGSSVNMT CLSQGFPAPK ILWSRQLPNG ELQPLSENAT LTLISTKMED SGVYLCEGIN QAGRSRKEVE LIIQVTPKDI KLTAFPSESV KEGDTVIISC TCGNVPETWI ILKKKAETGD TVLKSIDGAY TIRKAQLKDA GVYECESKNK VGSQLRSLTL DVQGRENNKD YFSPE