Recombinant humaan VCPKMT eiwit

VCPKMT is a protein-lysine N-methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity. Recombinant human VCPKMT protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Protein-lysine methyltransferase METTL21D, C14orf138, METTL21D, VCP-KMT

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

28.2 kDa (252aa) confirmed by MALDI-TOF

VCPKMT, Protein-lysine methyltransferase METTL21D, C14orf138, METTL21D, VCP-KMT, ATGP2903-10 µg, ATGP2903-20 µg, ATGP2903-50 µg, ATGP2903-100 µg, ATGP2903-250 µg, ATGP2903-500 µg, ATGP2903-1 mg, ATGP2903-10, ATGP2903-20, ATGP2903-50, ATGP2903-100, ATGP2903-250, ATGP2903-500, ATGP2903-1

Kernstock S., et al. (2012) Nat. Commun. 3:1038-1038.; ; Cloutier P., et al. (2013) PLoS Genet. 9:E1003210-E1003210.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid In. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Other

NP_078834

Q9H867

Human

MADTLES SLEDPLRSFV RVLEKRDGTV LRLQQYSSGG VGCVVWDAAI VLSKYLETPE FSGDGAHALS RRSVLELGSG TGAVGLMAAT LGADVVVTDL EELQDLLKMN INMNKHLVTG SVQAKVLKWG EEIEGFPSPP DFILMADCIY YEESLEPLLK TLKDISGFET CIICCYEQRT MGKNPEIEKK YFELLQLDFD FEKIPLEKHD EEYRSEDIHI IYIRKKKSKF PS