Recombinant humaan VISTA/B7-H5/PD-1H-eiwit

C10orf54, also known as Platelet receptor Gi24, is a member of the immunoglobulin superfamily. As a transmembrane molecule, this protein is expressed in bone on embryonic stem cells (ESCs), and on tumor cell surface. Thus, C10orf54 supports the differentiation of ESC and ehhances BMP4 induced signaling in ESC, but is also down regulated following BMP4 exposure. Recombinant human C10orf54, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

C10orf54, Stress-induced secreted protein-1, Sisp-1, B7-H5, B7H5, GI24, PP2135

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

19.1 kDa (170aa)

VISTA, B7-H5, PD1H, C10orf54, Stress-induced secreted protein-1, Sisp-1, B7-H5, B7H5, GI24, PP2135, ATGP3255-10 µg, ATGP3255-20 µg, ATGP3255-50 µg, ATGP3255-100 µg, ATGP3255-250 µg, ATGP3255-500 µg, ATGP3255-1 mg, ATGP3255-10, ATGP3255-20, ATGP3255-50, ATGP3255-100, ATGP3255-250, ATGP3255-500, ATGP3255-1

Lv Y et al., (2014) PLoS One 9 (1) :e86364.; ; Sakr MA et al., (2010) Cancer Sci. 101 (11) :2368-2374.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Cardiovascular

NP_071436

Q9H7M9

Human