Recombinant humaan Vitronectine-eiwit

Vitronectin, also known as VTN, is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. Increased expression of VTN, integrins and plasminogen activators has been observed in migrating cells during wound healing. Recombinant human VTN protein, fused to His-tag at N-terminus, was expressed in E. coli.

VTN, VN, S-protein, Serum-spreading factor, V75, Vitronectin V65 subunit, Vitronectin V10 subunit, Somatomedin-B, Somatomedin B, Complement S-protein

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

54.7 kDa (482aa)

VTN, Vitronectin precursor, V75, VN, VNT, ATGP2741-10 µg, ATGP2741-20 µg, ATGP2741-50 µg, ATGP2741-100 µg, ATGP2741-250 µg, ATGP2741-500 µg, ATGP2741-1 mg, ATGP2741-10, ATGP2741-20, ATGP2741-50, ATGP2741-100, ATGP2741-250, ATGP2741-500, ATGP2741-1

Chain D., et al. (1991) FEBS Lett. 285: 251-256.; ; Cherny R C., et al. (1993) J Biol Chem. 268: 9725-9729.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Cardiovascular

NP_000629

P04004

Human

MGSSHHHHHH SSGLVPRGSH MGSDQESCKG RCTEGFNVDK KCQCDELCSY YQSCCTDYTA ECKPQVTRGD VFTMPEDEYT VYDDGEEKNN ATVHEQVGGP SLTSDLQAQS KGNPEQTPVL KPEEEAPAPE VGASKPEGID SRPETLHPGR PQPPAEEELC SGKPFDAFTD LKNGSLFAFR GQYCYELDEK AVRPGYPKLI RDVWGIEGPI DAAFTRINCQ GKTYLFKGSQ YWRFEDGVLD PDYPRNISDG FDGIPDNVDA ALALPAHSYS GRERVYFFKG KQYWEYQFQH QPSQEECEGS SLSAVFEHFA MMQRDSWEDI FELLFWGRTS AGTRQPQFIS RDWHGVPGQV DAAMAGRIYI SGMAPRPSLA KKQRFRHRNR KGYRSQRGHS RGRNQNSRRP SRATWLSLFS SEESNLGANN YDDYRMDWLV PATCEPIQSV FFFSGDKYYR VNLRTRRVDT VDPPYPRSIA QYWLGCPAPG HL