Recombinant humaan XRCC2-eiwit

XRCC2 is a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. Recombinant human XRCC2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

X-ray repair cross complementing 2, X-ray repair complementing defective repair in Chinese hamster cells 2, FANCU, RAD51-like

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

34.3 kDa (303aa)

XRCC2, ADSF, RSTN, XCP1, FIZZ3, MGC126603, MGC126609, ATGP2509-10 µg, ATGP2509-20 µg, ATGP2509-50 µg, ATGP2509-100 µg, ATGP2509-250 µg, ATGP2509-500 µg, ATGP2509-1 mg, ATGP2509-010, ATGP2509-020, ATGP2509-050, ATGP2509-100, ATGP2509-250, ATGP2509-500, ATGP2509-01M

Masson J.Y., et al. (2001) Genes Dev. 15:3296-3307; ; Miller K.A., et al. (2002) J. Biol. Chem. 277:8406-8411

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Epigenomics (Transcription & Translation)

NP_005422

O43543

Human

MCSAFHR AESGTELLAR LEGRSSLKEI EPNLFADEDS PVHGDILEFH GPEGTGKTEM LYHLTARCIL PKSEGGLEVE VLFIDTDYHF DMLRLVTILE HRLSQSSEEI IKYCLGRFFL VYCSSSTHLL LTLYSLESMF CSHPSLCLLI LDSLSAFYWI DRVNGGESVN LQESTLRKCS QCLEKLVNDY RLVLFATTQT IMQKASSSSE EPSHASRRLC DVDIDYRPYL CKAWQQLVKH RMFFSKQDDS QSSNQFSLVS RCLKSNSLKK HFFIIGESGV EFC