Recombinant humaan XRCC3-eiwit

XRCC3, also known as RAD51-like, belongs to the RecA family and RAD51 subfamily. It participates in homologous recombination to maintain chromosome stability and repair DNA damage. This protein functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. Recombinant human XRCC3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

X-ray repair cross complementing protein 3, RAD51-like

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

40 kDa (366aa)

XRCC3, X-ray repair cross complementing protein 3, RAD51-like, ATGP1876-10 µg, ATGP1876-20 µg, ATGP1876-50 µg, ATGP1876-100 µg, ATGP1876-250 µg, ATGP1876-500 µg, ATGP1876-1 mg, ATGP1876-10, ATGP1876-20, ATGP1876-50, ATGP1876-100, ATGP1876-250, ATGP1876-500, ATGP1876-1

Tebbs RS. et al. (1995) Proc Natl Acad Sci u S A. 92:6354-6358.; ; Miller KA. et al. (2002) J Biol Chem. 277:8406-8411.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Epigenomics (Transcription & Translation)

NP_005423

O43542

Human

MDLDLLDLNP RIIAAIKKAK LKSVKEVLHF SGPDLKRLTN LSSPEVWHLL RTASLHLRGS SILTALQLHQ QKERFPTQHQ RLSLGCPVLD ALLRGGLPLD GITELAGRSS AGKTQLALQL CLAVQFPRQH GGLEAGAVYI CTEDAFPHKR LQQLMAQQPR LRTDVPGELL QKLRFGSQIF IEHVADVDTL LECVNKKVPV LLSRGMARLV VIDSVAAPFR CEFDSQASAP RARHLQSLGA TLRELSSAFQ SPVLCINQVT EAMEEQGAAH GPLGFWDERV SPALGITWAN QLLVRLLADR LREEEAALGC PARTLRVLSA PHLPPSSCSY TISAEGVRGT PGTQSH