Recombinant humaan ZNF346 eiwit

ZNF346 is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. ZNF346 may be involved in cell growth and survival. Recombinant human ZNF346 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Zinc finger protein 346, JAZ, Zfp346

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

35.3 kDa (317aa) confirmed by MALDI-TOF

ZNF346, Zinc finger protein 346, JAZ, Zfp346, ATGP2306-10 µg, ATGP2306-20 µg, ATGP2306-50 µg, ATGP2306-100 µg, ATGP2306-250 µg, ATGP2306-500 µg, ATGP2306-1 mg, ATGP2306-10, ATGP2306-20, ATGP2306-50, ATGP2306-100, ATGP2306-250, ATGP2306-500, ATGP2306-1

Schmitt J., et al. (2012) Int J Cancer. 131 (3) :673-82.; ; Yang M., et al. (1999) J Biol Chem. 274 (39) :27399-406.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT

Epigenomics (Transcription & Translation)

NP_036411

Q9UL40

Human

MGSSHHHHHH SSGLVPRGSH MGSMEYPAPA TVQAADGGAA GPYSSSELLE GQEPDGVRFD RERARRLWEA VSGAQPVGRE EVEHMIQKNQ CLFTNTQCKV CCALLISESQ KLAHYQSKKH ANKVKRYLAI HGMETLKGET KKLDSDQKSS RSKDKNQCCP ICNMTFSSPV VAQSHYLGKT HAKNLKLKQQ STKVEALHQN REMIDPDKFC SLCHATFNDP VMAQQHYVGK KHRKQETKLK LMARYGRLAD PAVTDFPAGK GYPCKTCKIV LNSIEQYQAH VSGFKHKNQS PKTVASSLGQ IPMQRQPIQK DSTTLED