Recombinant humaan/cysteel SDF-1/CXCL12-alfa-eiwit

SDF-1 is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12) . SDF-1 is strongly chemotactic for lymphocytes and works by its receptor CXCR4. The SDF-1+CXCR4 complex plays a significant role in the creation of metastases of neoplasms and as a response to cytostatic treatment. Identification of this complex may be a useful prognostic factor in the therapy of many types of carcinoma. Recombinant human/Feline SDF-1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

C-X-C motif chemokine ligand 12, Stromal cell-derived factor 1, C-X-C motif chemokine 12, Intercrine reduced in hepatomas, IRH, hIRH, Pre-B cell growth-stimulating factor, PBSF, SDF1, SDF1A, SDF1B, SCYB12, TLSF-a, TLSF-b, TPAR1

E.coli

Human, Feline

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

10.8 kDa (93aa) confirmed by MALDI-TOF

CXCL12, SDF1 a, Stromal cell-derived factor 1, SDF-1, Stromal cell-derived factor 1, CXCL12, PBSF, hIRH, Stromal cell-derived factor 1 C-X-C motif chemokine 12, OTTHuMP00000019491, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1, AI174028, Chemokine (C-X-C motif) ligand 12, Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1), Intercrine reduced in hepatomas IRH, Chemokine CXC motif ligand 12, SDF1A, SDF1B, Pre-B cell growth-stimulating factor, SCYB12, SDF 1, Stromal cell-derived factor 1 delta, SDF-1a, SDF-1b, Stromal cell-derived factor 1 gamma, Stromal cell-derived factor 1a, Stromal cell-derived factor-1 alpha, Thymic lymphoma cell-stimulating factor, Tlsf, TLSF-a, TLSF-b, Tlsfa, Tlsfb, TPAR1., ATGP0322-10 µg, ATGP0322-20 µg, ATGP0322-50 µg, ATGP0322-100 µg, ATGP0322-250 µg, ATGP0322-500 µg, ATGP0322-1 mg, ATGP0322-10, ATGP0322-20, ATGP0322-50, ATGP0322-100, ATGP0322-250, ATGP0322-500, ATGP0322-1

Arya M., et al. (2007) . Tumour Biol. 28 (3) :123-31.; ; Kucia M., et al. (2005) . Stem Cells. 23 (7) :879-94.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Hormones & Cytokines

NP_000600/NP_001009847.1

P48061/O62657

Human, Feline

MGSSHHHHHH SSGLVPRGSH MKPVSLSYRC PCRFFESHVA RANVKHLKIL NTPNCALQIV ARLKNNNRQV CIDPKLKWIQ EYLEKALNKR FKM