Recombinant Human IL-2 Receptor Subunit beta/IL-2RB/CD122 (C-6His)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Source : Human Cells; Human IL-2RB, also known asinterleukin-2 receptor subunit beta, is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein, and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.
Interleukin-2 receptor subunit beta, IL2RB, IL-2 receptor subunit beta, IL-2R subunit beta, High affinity IL-2 receptor subunit beta, CD122
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Ambient
Recombinant Human IL-2 receptor beta is produced by our Mammalian expression system and the target gene encoding Ala27-Asp239 is expressed with a 6His tag at the C-terminus.
Beschrijving
Source : Human Cells; Human IL-2RB, also known asinterleukin-2 receptor subunit beta, is the receptor for interleukin-2. IL2 receptor complex is involved in rec
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