Recombinant IGF1R/CD221 Monoklonale Antilichaam

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

IGF1R

P08069

Human

Recombinant Human IGF1R / CD221 protein

JTK; IGF1R; CD221; IGFIR; IGFR; JTK13; CD221 antigen; IGF-1R; IGF-I R; IGF-I receptor; IGF-IR; insulin-like growth factor 1 receptor

2C6

Unconjugated

FCM; ICC/IF

Signal Transduction; Cancer; Developmental Biology; Neuroscience; Cardiovascular; Metabolism

Protein A

1 mg/mL

ICC/IF 1:20-1:100; FCM 1:25-1:100

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/i79MWXLC

IgG