Recombinant IKB beta Monoklonale Antilichaam

IkB-beta a protein of the NF-kappa-B inhibitor family. IKB beta Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with IKB beta-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

IKB beta

Q15653

Human; Mouse

Recombinant human IKB beta fragment

TRIP; NFKBIB; IKBB; TRIP9; I kappa B beta; IkappaBbeta; I-kappa-B-beta; IKB beta; IkB-B; IkBbeta; IkB-beta; NF kappa BIB; NF-kappa-B inhibitor beta; NF-kappa-BIB; Thyroid receptor interacting protein 9; Thyroid receptor-interacting protein 9; TR interacting protein 9; TR-interacting protein 9; TRIP-9

A563

Unconjugated

WB; IF; FCM

Signal Transduction; Epigenetics and Nuclear Signaling; Immunology

Protein A purified

1 mg/mL

WB 1:500-1:1000; FCM 1:50-1:100; IF 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/X2IZjVwN

60 kDa

48 kDa

IgG, κ