Recombinant IL36B/IL1F8 Monoklonale antilichamen

Interleukin-1 family member 8 (IL1F8) also known as IL36B, is a member of the interleukin 1 (IL-1) cytokine family. IL1F8 may contain a 12-stranded beta-trefoil structure. Until recently, the IL-1 family of cytokines includes four members, with three having pro-inflammatory effects such as IL1F8 and the fourth member being an IL-1 receptor antagonist (IL-1Ra) . IL-1 family members exert their effects through binding to receptors that belong to the IL-1 receptor (IL-1R) family. IL1F8 exerts proinflammatory effects in primary human joint cells. Joint and serum IL-1F8 protein levels did not correlate with inflammation, but they were high in some human serum samples tested, including samples from patients with rheumatoid arthritis. IL1F8 also activated NK-κB.

IL36B

Q9D6Z6

Mouse

Recombinant Mouse IL36B/IL1F8 Protein

Il1f; Interleukin-1 family member; IL-1F; IL-1F8; Interleukin-1 family member 8; Interleukin-36 beta; Fil1e; Il1f8; Il36b

10A9

Unconjugated

WB

Protein A

1 mg/mL

WB 1:500-1:2000

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/JpssmVk1

21 kDa

25 kDa

IgG