Recombinant Keratine 20 Monoklonale Antilichaam

Keratin (cytokeratin) is an intermediate filament protein, which is mainly expressed in epithelial cells such as gastric epithelium and intestinal epithelium. Keratin heterodimers composed of acidic keratin (or type I keratin, keratin 9 to 23) and basic keratin (or type II keratin, keratin 1 to 8) assemble to form filaments. Keratin isoforms exhibit tissue- and differentiation-specific characteristics, making them useful as research biomarkers. Studies have shown that mutations in the keratin gene are related to skin diseases, liver and pancreatic diseases, and inflammatory bowel disease. Therefore, cytokeratin can be used as a tumor immunohistochemical marker.Keratin 20 (CK-20) is an essential intermediate filament component and the main cytoskeleton keratin of the intestinal epithelium. Studies have shown that keratin 20 is an important marker for colon cancer, liver cancer, and stomach cancer.

Keratin 20

P35900

Human; Rat; Mouse

Recombinant human Keratin 20 fragment

Cytokeratin; KRT; CD20; CK-20; CK20; K20; KRT21; KRT20; Cytokeratin 20; CD20; CK-20; CK20; K20; KRT21; KRT20; Cytokeratin 20

A277

Unconjugated

WB; IHC; IF; FCM

Signal Transduction; Cancer

Protein A purified

1 mg/mL

WB 1:500-1:2000; IHC 1:100-1:500; IF 1:50; FCM 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/8KrnVIzr

48 kDa

48 kDa

IgG, κ