Recombinant KIF5B Monoklonale Antilichaam

KIF5B is a member of kinesin superfamily protein 5 (KIF5) . KIF5 consists of three family members referred to as KIF5A, KIF5B, and KIF5C. KIF5A and KIF5C are specifically expressed in neurons whereas KIF5B is expressed ubiquitously. Targeted disruption of the kif5B gene resulted in embryonic lethality. These and other studies demonstrate that KIF5B plays an important role in the localization and distribution of major organelles, including the mitochondria and lysosome, and can contribute to autophagy. In addition, gene rearrangements involving KIF5B fusions to ALK and RET have been identified as drivers for lung cancer and other malignancies.

KIF5B

P33176

Human; Rat; Mouse

Recombinant human KIF5B fragment

HEL-S; KIF5B; HEL-S-61; KINH; KNS; KNS1; UKHC

A605

Unconjugated

WB; IHC

Signal Transduction

Protein A purified

1 mg/mL

WB 1:500-1:1000; IHC 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/sA708NzC

110 kDa

110 kDa

IgG, κ