Recombinant Lamin A/C Monoklonale Antilichaam

Lamin A/C (LMNA) Homo sapiens The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

Lamin A/C

P02545

Human; Mouse; Rat

Recombinant Human Lamin A/C protein

EMD; LDP; LMN; PRO; CDCD; LMNL; CMT2B; LMNA; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; LMNL1; MADA; PRO1; lamin; Lamin A/C;70 kDa lamin; Cardiomyopathy dilated 1A (autosomal dominant) ; Lamin A; Lamin A/C like 1; Lamin C; Lamin-A/C; Limb girdle muscular dystrophy 1B (autosomal dominant) ; LMN 1; LMN A; LMN C; Prelamin A/C; Renal carcinoma antigen NY REN 32; Renal carcinoma antigen NYREN32; Renal carcinoma antigen NY-REN-32; Lamin A/C (phospho Ser392)

2D5

Unconjugated

WB

Tags & Cell Markers; Signal Transduction; Cell Biology; Cancer

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/SyP2coyD

74 kDa,63 kDa

74 kDa,63 kDa

IgG, κ