Recombinant Latexine/LXN Monoklonale Antilichaam

Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI, and LXN, is a cytoplasm protein that belongs to the protease inhibitor I47 (latexin) family. It is highly expressed in the heart, prostate, ovary, kidney, pancreas, and colon. Latexin/LXN is the only known endogenous specific inhibitor of zinc-dependent metallocarboxypeptidases (MCPs) present in mammalians so far. Latexin is originally identified as a molecular marker for the regional specification of the neocortex in development in rats. The 222 amino acid latexin in the human shows different expression distribution with high levels in heart, prostate, ovary, kidney, pancreas, and colon, but only moderate or low levels in other tissues including the brain. Latexin is also expressed at high levels and is inducible in macrophages in concert with other protease inhibitors and potential protease targets, and thus is suggested to play a role in inflammation and innate immunity pathways. Despite the non-detectable sequence similarity with plant and parasite inhibitors, Latexin is related to a human putative tumor suppressor protein, TIG1. Also, Latexin is implicated in Alzheimer's disease.

LXN

Q9BS40

Human

Recombinant Human Latexin / LXN Protein

ECI; Endogenous carboxypeptidase inhibitor; Latexin; Latexin protein; MUM; Protein MUM; TCI; Tissue carboxypeptidase inhibitor; LXN

9B8

Unconjugated

WB; FCM; ICC/IF; IP

Immunology; Tags & Cell Markers; Cell Biology; Stem Cells

Protein A

1 mg/mL

WB 1:500-1:2000; FCM 1:25-1:100; ICC/IF 1:20-1:100; IP 4-6 μL/mg of lysate

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/y2c10bHl

25 kDa

25 kDa

IgG