Recombinant Lck Monoklonale Antilichaam

This gene is a member of the Src family of protein tyrosine kinases (PTKs) . The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described.

Lck

P06239

Human; Mouse; Rat

Recombinant Human Lck protein

IMD; LCK; IMD22; LSK; YT16; p56lck; pp58lck

3F5

Unconjugated

WB

Immunology; Signal Transduction

Protein A

0.2 mg/mL

WB 1:500-1:2000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/2RJBooNd

58 kDa

58 kDa

IgG, κ