Recombinant LEF1 monoklonaal antilichaam

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

LEF1

Q9UJU2

Human; Mouse; Rat

Recombinant Human LEF1 protein

TCF; TCF7L; LEF; LEF1; LEF-1; TCF10; TCF1ALPHA; TCF7L3; LEF-1

10F14

Unconjugated

WB

Epigenetics and Nuclear Signaling; Stem Cells; Cancer; Developmental Biology

Protein A

0.2 mg/mL

WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/pVMVXE5s

44 kDa

45-60 kDa

IgG, κ