Recombinant LysRS Monoklonale Antilichaam

Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA3 (Lys), the primer for reverse transcription initiation.

LysRS

Q15046

Human; Rat; Mouse

Recombinant human LysRS fragment

DFNB; KIAA; KARS; CMTRIB; DFNB89; KARS1; KARS2; KRS; EC 6.1.1.6; KARS 1; KARS 2; Lysine tRNA ligase; Lysine--tRNA ligase; LysRS; Lysyl-tRNA synthetase; SYK; KIAA0070

A291

Unconjugated

WB; IHC; IF; IP

Epigenetics and Nuclear Signaling

Protein A purified

1 mg/mL

WB 1:500-1:1000; IHC 1:50-1:100; IF 1:50; IP 1:25-1:50

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/wX3peWcs

75 kDa

75 kDa

IgG, κ