Recombinant Mouse VEGFC Proteïne (C-His Tag)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Vascular endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor (PDGF/VEGF) family. It is encoded in humans by the VEGFC gene, which is located on chromosome 4q34. The main function of VEGF-C is in lymphangiogenesis, where it acts on lymphatic endothelial cells (LECs) primarily via its receptor VEGFR-3 promoting survival, growth and migration. It was discovered in 1996 as a ligand for the orphan receptor VEGFR-3. Soon thereafter, it was shown to be a specific growth factor for lymphatic vessels in a variety of models. However, in addition to its effect on lymphatic vessels, it can also promote the growth of blood vessels and regulate their permeability. The effect on blood vessels can be mediated via its primary receptor VEGFR-3 or its secondary receptor VEGFR-2. Apart from vascular targets, VEGF-C is also important for neural development and blood pressure regulation. It has been suggested that VEGFC is a morphogen but not a chemotactic factor for lymphatic endothelial cell precursors.
Greater than 95% by SDS-PAGE
Lyophilized
0.2 μm filtered PBS, pH7.4
-70°C
Beschrijving
Vascular endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor (PDGF/VEG
Specificaties
Recent bekeken producten
ExactaCruz® Pipette Tip Reload System, 50-1250 μl, case
sc-201714
80 Racks/Case
Disc Membrane Hydrophobic PTFE, 0.22μm
CPTB14222
50 PCS
Rat Serum Albumin
CSB-NP000101r-01
1 mg
Denhardt's Solution (50X)
EC-915
50 mL
FKBP4, ID (FK506-binding Protein 4, Peptidyl-prolyl cis-trans Isomerase FKBP4, PPIase FKBP4, Rotamase, HSP-binding Immunophilin, HBI, FKBP52 Protein, 52kD FK506-binding Protein, 52kD FKBP, FKBP-52, 59kD Immunophilin, FKBP59, p59 Protein, FKBP-4, FKBP52)
MBS623609-01
0.2 mL
West Nile Virus, NS3 Protease (WNV)
MBS603723-01
0.1 mg
Human Sertoli Cell Complete Medium
MBS2576755-01
100 mL
Urobilinogen protein
MBS5303823-01
100 mg
Recent gezochte producten
ExactaCruz® Pipette Tip Reload System, 50-1250 μl, case
sc-201714
80 Racks/Case
Cbp 3'UTR Luciferase Stable Cell Line
TU201714
1.0 mL
Mouse Gpx2 activation kit by CRISPRa
GA201714
1 Kit
CCDC50 Human qPCR Template Standard (NM_174908)
HK201714
1 Kit
Prpsap2 Mouse qPCR Template Standard (NM_144806)
MK201714
1 Kit
Horse Prekallikrein Affinity Purified
B2017141
50 µg
Human Recombinant Activin A
B2017149
10 µg
Mouse Alpha-N-acetyl-neuraminyl-2, 3-beta-galactosyl-1, 3-N-acetyl-galactosaminide alpha-2, 6-sialyltransferase (ST6GALNAC4) ELISA Kit
MBS7201714-01
48 Well