Recombinant MSH6/GTBP Monoklonale Antilichaam

This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.

MSH6

P52701

Human; Cynomolgus; Mouse; Rat; Ferret

A synthetic peptide corresponding to the center region of the Human MSH6 / GTBP

MSH; mutS homolog; HNPCC; MSH6; GTBP; GTMBP; HNPCC5; HSAP; p160; mutS homolog 6; GTBP; GTMBP; HNPCC5; HSAP; mutS homolog 6; p160

8B1

Unconjugated

IHC-P; ICC/IF

Epigenetics and Nuclear Signaling

Protein A

1 mg/mL

IHC-P 1:100-1:500; ICC/IF 1:20-1:100

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/tu2cHzy7

IgG