Recombinant muis 4-1BB/CD137/TNFRSF9 eiwit

TNFRSF9, also known as tumor necrosis factor receptor superfamily member 9, interacts with TNFSF9 expressed on activated T cells and delivers a co-stimulatory signal for T cell activation and growth. It binds with high affinity to the transmembrane TNFSF9 (4-1BB ligand) which expressed on antigen presenting cells and myeloid progenitor cells. Recombinant mouse TNFRSF9, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD137, ly63

Baculovirus

Mouse

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

18.6 kDa (172aa)

41BB, TNFRSF9, Tnfrsf9, 4-1BB ligand receptor, T-cell antigen 4-1BB, CD antigen: CD137, Cd137, Ila, Ly63, ATGP3199-10 µg, ATGP3199-20 µg, ATGP3199-50 µg, ATGP3199-100 µg, ATGP3199-250 µg, ATGP3199-500 µg, ATGP3199-1 mg, ATGP3199-10, ATGP3199-20, ATGP3199-50, ATGP3199-100, ATGP3199-250, ATGP3199-500, ATGP3199-1

Chalupny NJ et al., (1992) Proc. Natl. Acad. Sci. U.S.A. 89 (21) :10360-10364.; ; Martinez Gomez JM et al., (2013) PLoS ONE 8 (9) :E73277.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Apoptosis

NP_035742

P20334

Mouse

VQNSCDNCQP GTFCRKYNPV CKSCPPSTFS SIGGQPNCNI CRVCAGYFRF KKFCSSTHNA ECECIEGFHC LGPQCTRCEK DCRPGQELTK QGCKTCSLGT FNDQNGTGVC RPWTNCSLDG RSVLKTGTTE KDVVCGPPVV SFSPSTTISV TPEGGPGGHS LQVLLEHHHH HH