Recombinant muis ACBP/DBI-eiwit

Acbp, also known as Acyl-CoA-binding protein isoform 2, is a diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulatesignal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. Expression of Acbp is significantly induced during adipocyte differentiation. Acbp acts as an acyl-CoA pool former and regulates long-chain fatty acids (LCFA) metabolism in peripheral tissues. Recombinant mouse Acbp protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Acyl-CoA-binding protein, ACBP, Diazepam-binding inhibitor, DBI, Endozepine, EP

E.coli

Mouse

His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

> 95% by SDS-PAGE

12.4 kDa (110aa) confirmed by MALDI-TOF

Acbp, Acyl-CoA-binding protein isoform 2, ACBD1, Acbp, endozepine, EP, ATGP3751-10 µg, ATGP3751-20 µg, ATGP3751-50 µg, ATGP3751-100 µg, ATGP3751-250 µg, ATGP3751-500 µg, ATGP3751-1 mg, ATGP3751-10, ATGP3751-20, ATGP3751-50, ATGP3751-100, ATGP3751-250, ATGP3751-500, ATGP3751-1

Bouyakdan K., et al. (2015) J Neurochem. 133 (2) :253-65.; ; Manjithaya R., et al. (2010) J Cell Biol. 188 (4) :537-46.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Neuroscience

NP_031856

P31786

Mouse

MGSSHHHHHH SSGLVPRGSH MGSMSQAEFD KAAEEVKRLK TQPTDEEMLF IYSHFKQATV GDVNTDRPGL LDLKGKAKWD SWNKLKGTSK ESAMKTYVEK VDELKKKYGI