Recombinant muis BMP-14/GDF-5 eiwit

Growth/differentiation factor 5 precursor, also known as GDF5, is a member of the TGF superfamily. GDF5 has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. GDF5mutations have been identified in mice with the mutation brachypodism (bp), a mutation which affects the length and number of bones in limbs. Recombinant mouse GDF5 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Growth differentiation factor 5, CDMP-1, Cartilage-derived morphogenetic protein 1, BRP, BP, Bone morphogenetic protein 14, BMP-14

E.coli

Mouse

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

16 kDa (143aa)

Growth/differentiation factor 5 precursor, Growth differentiation factor 5, GDF5, CDMP-1, Cartilage-derived morphogenetic protein 1, BRP, BP, Bone morphogenetic protein 14, BMP-14, BMP14, BMP 14, ATGP2894-10 µg, ATGP2894-20 µg, ATGP2894-50 µg, ATGP2894-100 µg, ATGP2894-250 µg, ATGP2894-500 µg, ATGP2894-1 mg, ATGP2894-010, ATGP2894-020, ATGP2894-050, ATGP2894-100, ATGP2894-250, ATGP2894-500, ATGP2894-01M

Katayama R., et al. (2004) Rheumatology. 43: 980-985.; ; Kwong F N., et al. (2008) J Orthop Res. 27: 752-757.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Hormones & Cytokines

NP_032135

P43027

Mouse

MGSSHHHHHH SSGLVPRGSH MGSAPLANRQ GKRPSKNLKA RCSRKALHVN FKDMGWDDWI IAPLEYEAFH CEGLCEFPLR SHLEPTNHAV IQTLMNSMDP ESTPPTCCVP TRLSPISILF IDSANNVVYK QYEDMVVESC GCR