Recombinant muis Cathepsin S-eiwit

Ctss, as known as cathepsin S isoform 2, is a lysosomal cysteine protease of the papain family. This protein plays a major role in the processing of the MHC class II-associated invariant chain. It has been implicated in the pathogenensis of several diseases such as Alzheimer s disease and degenerative disorders associated with the cells of the mononuclear phagocytic system. Also, it is less abundant in tissues than Cathepsins B, L and H. The highest levels of this protein have been found in lymph nodes, spleen and phagocytic cells. Recombinant mouse Ctss, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Cathepsin S isoform 2, Ctss, Cathepsin S, Cats

Baculovirus

Mouse

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

36.9 kDa (325aa)

Ctss, ATGP3349-10 µg, ATGP3349-20 µg, ATGP3349-50 µg, ATGP3349-100 µg, ATGP3349-250 µg, ATGP3349-500 µg, ATGP3349-1 mg, ATGP3349-10, ATGP3349-20, ATGP3349-50, ATGP3349-100, ATGP3349-250, ATGP3349-500, ATGP3349-1

Zhao P., et al. (2014) J. Biol. Chem. 289:27215-27234.; ; Lafarge JC., et al. (2014) Diabetologia. 57:1674-1683.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_067256

O70370

Mouse

Val21