Recombinant muis Cathepsine E-eiwit

CTSE, also known as cathepsin E, belongs to an intracellular aspartic protease of the pepsin family. It plays an important role in the degradation of proteins, the generation of bioactive proteins, and antigen processing. It is efficient in cleaving the Swedish mutant of amyloid precursor protein (APP) at the B site but show almost on reactivity with the wild-type APP. Recombinant mouse CTSE, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

CTSE, A430072003Rik, C920004C08Rik, CatE, CE

Baculovirus

Mouse

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

41.8 kDa (385aa)

Cathepsin E, CTSE, A430072003Rik, C920004C08Rik, CatE, CE, ATGP3279-10 µg, ATGP3279-20 µg, ATGP3279-50 µg, ATGP3279-100 µg, ATGP3279-250 µg, ATGP3279-500 µg, ATGP3279-1 mg, ATGP3279-10, ATGP3279-20, ATGP3279-50, ATGP3279-100, ATGP3279-250, ATGP3279-500, ATGP3279-1

Tsukuba T., et al. (2000) Mol. Cells 10:601-611.; ; Bennett K., et al. (1992) Eur. J. Immunol. 22: 1519-1524.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_031825

P70269

Mouse

ALHRVPLRRH QSLRKKLRAQ GQLSEFWRSH NLDMTRLSES CNVYSSVNEP LINYLDMEYF GTISIGTPPQ NFTVIFDTGS SNLWVPSVYC TSPACKAHPV FHPSQSDTYT EVGNHFSIQY GTGSLTGIIG ADQVSVEGLT VDGQQFGESV KEPGQTFVNA EFDGILGLGY PSLAAGGVTP VFDNMMAQNL VALPMFSVYL SSDPQGGSGS ELTFGGYDPS HFSGSLNWIP VTKQAYWQIA LDGIQVGDTV MFCSEGCQAI VDTGTSLITG PPDKIKQLQE AIGATPIDGE YAVDCATLDT MPNVTFLINE VSYTLNPTDY ILPDLVEGMQ FCGSGFQGLD IPPPAGPLWI LGDVFIRQFY SVFDRGNNQV GLAPAVPLEH HHHHH