Recombinant muis Cathepsine Z-eiwit

Cathepsin X/Z/P, also known as cathepsin Z/X, is a relatively new cysteine protease of the papain family. Compared to other members of the papain family, It has a short proregion and unique insertions. Acting as a carboxypeptidase, It displays a unique specificity. Recombinant mouse Cathepsin X/Z/P, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques

Specific activity is > 3,000 pmol/min/ug in which one unit will convert 1.0 pmole of Mca-PLGL-Dpa-AR-NH2 to MCA- Pro-Leu-OH per minute at pH 3.5 at 25C

Cathepsin X/Z/P, CTSZ, AI787083, AU019819, CTSX, D2Wsu143e

Baculovirus

Mouse

His-Tag

SDS-PAGE, Enzyme Activity

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

Specific activity is > 3,000pmol/min/ug in which one unit will convert 1.0pmole of Mca-PLGL-Dpa-AR-NH2 to MCA- Pro-Leu-OH per minute at pH 3.5 at 25C

32.8 kDa (292aa)

Cathepsin X, Z, P, ATGP3877-10 µg, ATGP3877-20 µg, ATGP3877-50 µg, ATGP3877-100 µg, ATGP3877-250 µg, ATGP3877-500 µg, ATGP3877-1 mg, ATGP3877-10, ATGP3877-20, ATGP3877-50, ATGP3877-100, ATGP3877-250, ATGP3877-500, ATGP3877-1

Santamaria., et al. (1998) J. Biol. Chem. 273:16816-16823. ; ; Menard., et al. (2001) Biol. Chem. 382:839-845.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cancer

NP_071720

Q9WUU7

Mouse

Ala23