Recombinant muis CCL21/6Ckine-eiwit

CCL21, also known as C-C motif chemokine 21a, is a member of homeostatic chemokine. It plays an importantrole in adaptive immune responses and inflammation. This protein Inhibits hemopoiesis and stimulates chemotaxis.It is involved in signaling through CXCR3. This protein is upregulated on local vascular endothelial cells, macrophages, T cells, and neurons during chronic inflammation or tissue damage. Deficient of This protein was impaired in the medullary deletion of self-reactive thymocytes and developed autoimmune dacryoadenitis and T cellaccumulation in the lymph nodes was also defective. Recombinant mouse CCL21, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

C-C motif chemokine ligand 21A, 6Ckine, Beta-chemokine exodus-2, Small-inducible cytokine A21a, Scya21, Scya21a, Thymus-derived chemotactic agent 4, TCA4, 6CKBAC2, ALP, CKb9, Gm1987, SLC

Baculovirus

Mouse

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

13.1 kDa (119aa)

CCL21Ckine, ATGP3900-10 µg, ATGP3900-20 µg, ATGP3900-50 µg, ATGP3900-100 µg, ATGP3900-250 µg, ATGP3900-500 µg, ATGP3900-1 mg, ATGP3900-10, ATGP3900-20, ATGP3900-50, ATGP3900-100, ATGP3900-250, ATGP3900-500, ATGP3900-1

Kozai M., et al. (2017) J Exp Med. 214:1925-1935. ; ; Chen SC., et al. (2002) J Immunol. 168:1001-1008.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_035254

P84444

Mouse

Ala

SDGGGQD CCLKYSQKKI PYSIVRGYRK QEPSLGCPIP AILFSPRKHS KPELCANPEE GWVQNLMRRL DQPPAPGKQS PGCRKNRGTS KSGKKGKGSK GCKRTEQTQP SRG