Recombinant muis CD14 eiwit

Cd14, also known as monocyte differentiation antigen CD14, is a component of the innate immune system. This protein was found expressed in macrophages, neutrophil granulocyte and dendritic cells. It exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol tail (mCD14), the other a soluble form (sCD14) . The major function is serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns. Recombinant Mouse Cd14, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Monocyte differentiation antigen CD14, CD14 molecule, Myeloid cell-specific leucine-rich glycoprotein

Baculovirus

Mouse

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

38.3 kDa (357aa)

CD14, ATGP3175-10 µg, ATGP3175-20 µg, ATGP3175-50 µg, ATGP3175-100 µg, ATGP3175-250 µg, ATGP3175-500 µg, ATGP3175-1 mg, ATGP3175-10, ATGP3175-20, ATGP3175-50, ATGP3175-100, ATGP3175-250, ATGP3175-500, ATGP3175-1

Ferrero E., et al. (1990) J Immunol. 45 (1) :331-336.; ; SD Wright., et al. (1990) Science. 249:1431-1433.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_033971

P10810

Mouse