Recombinant muis CD36/SR-B3-eiwit

CD36, also known as platelet glycoprotein 4, is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types. As a member of the scavenger receptor family, CD36 is a multiligand pattern recognition receptor that interacts with a large number of structurally dissimilar ligands. It plays a role in lipid metabolism and has been identified as a fatty acid translocase necessary for the binding and transport of LCFA in cells and tissues. It also plays a significant role in the initiation and pathogenesis of chronic inflammatory diseases such as Alzheimer s disease and atherosclerosis. It is an integral membrane protein primarily serving as receptors for thrombospondin and collagen and by the erythrocytes infected with the human malaria parasite. Recombinant mouse CD36, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Cd36, CD36 antigen, FAT, GPIV, Scarb3

Baculovirus

Mouse

His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

47.4 kDa (419aa)

CD36, SR-B3, ATGP3210-10 µg, ATGP3210-20 µg, ATGP3210-50 µg, ATGP3210-100 µg, ATGP3210-250 µg, ATGP3210-500 µg, ATGP3210-1 mg, ATGP3210-10, ATGP3210-20, ATGP3210-50, ATGP3210-100, ATGP3210-250, ATGP3210-500, ATGP3210-1

Febbraio M., et al. (2001) J. Clin. Invest. 108:785-791.; ; Armstrong LC., et al. (2003) Matrix Biol. 22:63-71.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_031669

Q08857

Mouse

GDMLIEK TIKREVVLEE GTTAFKNWVK TGTTVYRQFW IFDVQNPDDV AKNSSKIKVK QRGPYTYRVR YLAKENITQD PEDHTVSFVQ PNGAIFEPSL SVGTEDDNFT VLNLAVAAAP HIYQNSFVQV VLNSLIKKSK SSMFQTRSLK ELLWGYKDPF LSLVPYPIST TVGVFYPYND TVDGVYKVFN GKDNISKVAI IESYKGKRNL SYWPSYCDMI NGTDAASFPP FVEKSRTLRF FSSDICRSIY AVFGSEIDLK GIPVYRFVLP ANAFASPLQN PDNHCFCTEK VISNNCTSYG VLDIGKCKEG KPVYISLPHF LHASPDVSEP IEGLHPNEDE HRTYLDVEPI TGFTLQFAKR LQVNILVKPA RKIEALKNLK RPYIVPILWL NETGTIGDEK AEMFKTQVTG KIK