Recombinant muis EphA4-eiwit

Epha4, as known as ephrin type-A receptor 4, is a single-pass type 1 membrane protein which belongs to the protein kinase superfamily and ephrin receptor subfamily. This protein may play a role in a signal transduction process involved in hindbrain pattern formation. The ephrins and ephrin receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Recombinant mouse Epha4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques

EPH receptor A4, Ephrin type-A receptor 4, Tyrosine-protein kinase receptor MPK-3, Tyrosine-protein kinase receptor SEK-1, Cek8, Hek8, rb, Sek, Tyro1

Baculovirus

Mouse

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

59.3 kDa (536aa)

EphA4, Ephrin type-A receptor 4 , Epha4, 2900005c20Rik, AI385584, Cek8, Hek8, rb, Sek, Sek1, Tyro1, ATGP3403-10 µg, ATGP3403-20 µg, ATGP3403-50 µg, ATGP3403-100 µg, ATGP3403-250 µg, ATGP3403-500 µg, ATGP3403-1 mg, ATGP3403-10, ATGP3403-20, ATGP3403-50, ATGP3403-100, ATGP3403-250, ATGP3403-500, ATGP3403-1

Borgius L., et al. (2014) J. Neurosci. 34:3841-3853.; ; Steinecke A., et al. (2014) Development 141:460-471.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_031962

Q03137

Mouse

Val20

VTGSRVYPAN EVTLLDSRSV QGELGWIASP LEGGWEEVSI MDEKNTPIRT YQVCNVMEAS QNNWLRTDWI TREGAQRVYI EIKFTLRDCN SLPGVMGTCK ETFNLYYYES DNDKERFIRE SQFGKIDTIA ADESFTQVDI GDRIMKLNTE IRDVGPLSKK GFYLAFQDVG ACIALVSVRV FYKKCPLTVR NLAQFPDTIT GADTSSLVEV RGSCVNNSEE KDVPKMYCGA DGEWLVPIGN CLCNAGHEEQ NGECQACKIG YYKALSTDAS CAKCPPHSYS VWEGATSCTC DRGFFRADND AASMPCTRPP SAPLNLISNV NETSVNLEWS SPQNTGGRQD ISYNVVCKKC GAGDPSKCRP CGSGVHYTPQ QNGLKTTRVS ITDLLAHTNY TFEIWAVNGV SKYNPSPDQS VSVTVTTNQA APSSIALVQA KEVTRYSVAL AWLEPDRPNG VILEYEVKYY EKDQNERSYR IVRTAARNTD IKGLNPLTSY VFHVRARTAA GYGDFSEPLE VTTNTVPSRI IGDGANSTLE HHHHHH