Recombinant muis FGF-21 eiwit

FGF21, also known as fibroblast growth factor 21, is a member of the fibroblast growth factor family. It has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. It stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression. Recombinant mouse FGF21, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Fibroblast growth factor 21

Baculovirus

Mouse

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

21kDa (190aa)

FGF21, Fibroblast growth factor 21, ATGP3300-10 µg, ATGP3300-20 µg, ATGP3300-50 µg, ATGP3300-100 µg, ATGP3300-250 µg, ATGP3300-500 µg, ATGP3300-1 mg, ATGP3300-10, ATGP3300-20, ATGP3300-50, ATGP3300-100, ATGP3300-250, ATGP3300-500, ATGP3300-1

Kharitonenkov A., et al. (2005) J Clin Invest. 115:1627-1635.; ; Yamauchi H., et al. (2006) EMBO Rep. 7:649-654.

Goto T, et al. The hepatokine FGF21 is crucial for peroxisome proliferator-activated receptor-α agonist-induced amelioration of metabolic disorders in obese mice. (J Biol Chem. 2017) {https://pubmed.ncbi.nlm.nih.gov/28404815/}

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Angiogenesis

NP_064397

Q9JJN1

Mouse

Ala29