Recombinant muis Folaathydrolase 1/FOLH1-eiwit

Folh1, as known as glutamate carboxypeptidase 2, is a single pass type 2 membrane protein which belongs to the peptidase M28 family and M28B subfamily. This protein is most highly expressed in prostate epithelium. It is detected in urinary bladder, kidney, testis, ovary, live, stomach, small intestine colon, and the capillary endothelium of a variety of tumors. Thus, it shows a promising role in directed imaging and therapy of recurrent of metastatic disease. Recombinant mouse Folh1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Pteroylpoly-gamma-glutamate carboxypeptidase, Prostate-specific membrane antigen homolog, N-acetylated-alpha-linked acidic dipeptidase I, NAALADase I, Naalad1, Mopsm, mGCP, Membrane glutamate carboxypeptidase, Glutamate carboxypeptidase II, Glutamate carboxypeptidase 2, GCPII, Folylpoly-gamma-glutamate carboxypeptidase, FGCP

Baculovirus

Mouse

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 85% by SDS-PAGE

80.5 kDa (717aa)

Folh1, Glutamate carboxypeptidase 2 isoform 1, Folh1, GCP2, mopsm, ATGP3357-10 µg, ATGP3357-20 µg, ATGP3357-50 µg, ATGP3357-100 µg, ATGP3357-250 µg, ATGP3357-500 µg, ATGP3357-1 mg, ATGP3357-10, ATGP3357-20, ATGP3357-50, ATGP3357-100, ATGP3357-250, ATGP3357-500, ATGP3357-1

Rahn KA., et al, (2012) Proc. Natl. Acad. Sci. U.S.A. 109:20101-20106.; ; Schaevitz LR., et al, (2012) Dev Neurobiol 72:891-905.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Signal Transduction

NP_058050

O35409

Mouse

Ala

ADPKPSNEAT GNVSHSGMKK EFLHELKAEN IKKFLYNFTR TPHLAGTQNN FELAKQIHDQ WKEFGLDLVE LSHYDVLLSY PNKTHPNYIS IINEDGNEIF KTSLSEQPPP GYENISDVVP PYSAFSPQGT PEGDLVYVNY ARTEDFFKLE REMKISCSGK IVIARYGKVF RGNMVKNAQL AGAKGMILYS DPADYFVPAV KSYPDGWNLP GGGVQRGNVL NLNGAGDPLT PGYPANEHAY RHELTNAVGL PSIPVHPIGY DDAQKLLEHM GGPAPPDSSW KGGLKVPYNV GPGFAGNFST QKVKMHIHSY TKVTRIYNVI GTLKGALEPD RYVILGGHRD AWVFGGIDPQ SGAAVVHEIV RSFGTLKKKG RRPRRTILFA SWDAEEFGLL GSTEWAEEHS RLLQERGVAY INADSSIEGN YTLRVDCTPL MYSLVYNLTK ELQSPDEGFE GKSLYDSWKE KSPSPEFIGM PRISKLGSGN DFEVFFQRLG IASGRARYTK NWKTNKVSSY PLYHSVYETY ELVVKFYDPT FKYHLTVAQV RGAMVFELAN SIVLPFDCQS YAVALKKYAD TIYNISMKHP QEMKAYMISF DSLFSAVNNF TDVASKFNQR LQELDKSNPI LLRIMNDQLM YLERAFIDPL GLPGRPFYRH IIYAPSSHNK YAGESFPGIY DALFDISSKV NASKAWNEVK RQISIATFTV QAAAETLREV AHHHHHH